Revolutionizing skincare through innovative lymphatic science.
IRÄYE is the first skincare brand based on lymphatic science—built on one truth: skin longevity starts with the lymphatic system.
What is the Lymphatic System
The Body’s natural toxin filter
The Lymphatic system is a network of clear tubes laying almost invisible under the surface of the skin collecting and removing unwanted skin waste accumulated through daily life and transporting cleansing lymph fluid, nutrients and infection fighting white blood cells around the body, so our vital systems can function at their best.
What does the facial Lymphatic System do
Naturally removes toxic skin waste
Delaying collagen and elastic fiber breakdown
Inhibits inflammation
Enhancing skin’s natural regeneration potential
Drains excess fluid
Resulting in depuffed, sculpted skin
Protects against ageing
Combining all actions above
How the Lymphatic System responds to aging and environmental stressors
Although the lymphatic system operates spontaneously throughout every living moment, the lymphatic system’s delicate vessels are easily damaged by inflammation, UV light and the aging process.
Over time, these vessels decline in both number and activity whilst also structurally decaying, leaking some of their contents back into the skin.
This causes an increase in water retention and a build-up of toxins, hindering the skin's performance and accelerating the visible signs of aging.
A breakthrough discovery
In a combined career spanning over 40 years and some of the world’s most respected research institutions, Professor Detmar and Dr. Gousopoulos have been instrumental in the rediscovery of the importance of lymphatics.
By studying over 2,200 natural extracts, they identified five plant-derived actives and developed the LYMPHACTIVE™ Complex—IRÄYE’s proprietary technology. With IRÄYE, they bring lymphatic science to skincare for the very first time, through formulas designed to support healthy-looking, radiant skin.
How the Lymphactive Complex™ works to repair the problem
The human lymphatic system runs on chemical signals that trigger its cleansing impulses and self-repairing functions.
While the strength and frequency of these signals can fade over time, Lymphactive™ Complex helps to enhance and support these signals.
The first signal reawakens the vessels themselves, triggering the rhythmic muscle cell contractions that push lymph fluid through the lymphatic system and increase its cleansing action.
The second signal instigates the lymphatic system’s natural repair mechanisms. Improved condition and strength increases each vessel’s capacity and efficiency as they transport lymph fluid through the dermal layers.
VISIBLE RESULTS
Each IRÄYE product is formulated through the lens of lymphatic science—the starting point of skin longevity. Powered by the LYMPHACTIVE™ Complex, our formulas are designed to support healthy-looking, balanced skin, helping the complexion look fresher, more even, and more radiant over time. With consistent use, skin feels comfortable and looks smoother, and the visible signs of ageing appear softened.
Brighter and more radiant skin
Visibly calms the look of redness
Reduces the appearance of puffiness and swelling
Brighter and more radiant skin
Visibly calms the look of redness
Reduces the appearance of puffiness and swelling
By screening over 2,200 plant extracts, they achieved the breakthrough discovery of the first natural lymphatic activators, extracts that stimulate lymphatic function and the body’s ability to repair damaged lymph vessels.
Healthy skin works smarter and looks better
Pioneering lymphatic research
Our Founders, Professor Michael Detmar and Dr. Epameinondas Gousopoulos are leading figures in lymphatic medicine. With over four decades of combined experience at prestigious medical institutions and more than 300 published works, they have significantly advanced our understanding of the lymphatic system's role in human health.
Prof. Michael Detmar
Current Positions
Professor of Pharmacogenomics, ETH Zurich, Institute of Pharmaceutical Sciences
Co-founder and Chief Scientific Officer at IRAYE Skincare
Visiting Professorships
Visiting Professor, Kitasato University, Japan (2018-present)
Visiting Professor of Pathology and of Dermatology, Harvard Medical School, Boston, USA (1993-1997)
Notable Roles
Election to the German National Academy of Sciences Leopoldina
Associate Professor of Dermatology, Harvard Medical School, Boston, USA
Assistant Professor of Dermatology, Steglitz Medical Center, Free University of Berlin
Elected member, Research Council of the Swiss National Science Foundation
Awards
2005 - Marion B. Sulzberger Memorial Award and Lectureship, American Academy of Dermatology
2006 - Jeffrey Schechner Memorial Lecture, Yale University
2007 - Rudi Kormane Lectureship, European Society for Dermatological Research
2020 - Lifetime Achievement Award in the field of Lymphatics from the Lymphatic Education and Research Network, USA
Current Positions
Resident and Principle Investigator, Clinic for Plastic and Hand Surgery, University Hospital Zürich
Co-founder and President of the Board of Directors at IRAYE Skincare
Notable Roles
PhD Thesis (Dr. Sc.) with Prof. Michael Detmar, Institute of Pharmaceutical Sciences, ETH Zurich
Medical training (M.D. degree) Aristotle University of Thessaloniki, Greece and Georg August Universität Göttingen, Germany
Awards
2021 - Filling the Gap Award, University of Zurich
2021 - Research Award, 57th Swiss Plastic Surgery Annual Meeting
2020 - Principal Investigator Award, Lipedema Foundation
2016 - 6th World Symposium for Lymphedema Surgery, Barcelona, Spain (invited inaugural keynote lecturer)
