Revolutionizing skincare through innovative lymphatic science.

IRÄYE supports the skin's lymphatic system to deliver a three-fold effect of PURIFYING the skin, BOOSTING lymphatic function and PROTECTING the condition of the skin and its lymph vessels.

1

What is the Lymphatic System

The Body’s natural toxin filter

The Lymphatic system is a network of clear tubes laying almost invisible under the surface of the skin collecting and removing unwanted skin waste accumulated through daily life and transporting cleansing lymph fluid, nutrients and infection fighting white blood cells around the body, so our vital systems can function at their best.

2

What does the facial Lymphatic System do

Naturally removes toxic skin waste

Delaying collagen and elastic fiber breakdown

Inhibits inflammation

Enhancing skin’s natural regeneration potential

Drains excess fluid

Resulting in depuffed, sculpted skin

Protects against ageing

Combining all actions above

3

How the Lymphatic System responds to aging and environmental stressors

Although the lymphatic system operates spontaneously throughout every living moment, the lymphatic system’s delicate vessels are easily damaged by inflammation, UV light and the aging process.

Over time, these vessels decline in both number and activity whilst also structurally decaying, leaking some of their contents back into the skin.



This causes an increase in water retention and a build-up of toxins, hindering the skin's performance and accelerating the visible signs of aging.

4

A breakthrough 
discovery

In a combined career spanning over 40 years and some of the world’s most respected research institutions, Professor Detmar and Dr. Gousopoulos have been instrumental in the rediscovery of the importance of lymphatics.

By studying over 2,000 natural extracts they were able to identify a series of activators capable of stimulating both lymphatic activity and the body’s natural repair and renewal systems.
It is with IRÄYE and the five plant-derived actives in Lymphactive™ Complex, that they are bringing cutting edge science of lymphatics to skincare for the very first time.

5

How the Lymphactive Complex™ works to repair the problem

The human lymphatic system runs on chemical signals that trigger its cleansing impulses and self-repairing functions.

While the strength and frequency of these signals can fade over time, Lymphactive™ Complex helps to enhance and support these signals.

The first signal reawakens the vessels themselves, triggering the rhythmic muscle cell contractions that push lymph fluid through the lymphatic system and increase its cleansing action.

The second signal instigates the lymphatic system’s natural repair mechanisms. Improved condition and strength increases each vessel’s capacity and efficiency as they transport lymph fluid through the dermal layers.

VISIBLE RESULTS

Each IRÄYE product is formulated with results and efficacy in mind. The Lymphactive™ Complex supports improved skin function after only a few days and boosts the skins natural detox system by +250%*. The cumulative benefits of ongoing use contribute to a lasting radiant appearance, skin that looks and feels healthier, and noticeable slowing of the visible signs of aging.

shop IRÄYE PRODUCTS
shop IRÄYE PRODUCTS
Before
Before
After
After
2
weeks

Enhanced lymphatic activity flushes toxins and debris from the skin for a brighter-looking tone and more radiant appearance.

4
weeks

Increased activity combined with improved vessel function begins to reduce the visible appearance of inflammation and redness.

8
weeks

An improved skin environment supports cell turnover, helping the skin to appear sculpted and resurfaced. Effective drainage and detoxification minimises the appearance of puffiness and swelling.

The science of radiance

By screening over 2,200 plant extracts, they achieved the breakthrough discovery of the first natural lymphatic activators, extracts that stimulate lymphatic function and the body’s ability to repair damaged lymph vessels.

Health
Before
Beauty

Healthy skin works smarter and looks better

Pioneering lymphatic research

Our Founders, Professor Michael Detmar and Dr. Epameinondas Gousopoulos are leading figures in lymphatic medicine. With over four decades of combined experience at prestigious medical institutions and more than 300 published works, they have significantly advanced our understanding of the lymphatic system's role in human health.

Discover the science
Discover the science
21+
Research awards
40+
Years of research
300+
Peer reviewed

papers
10+
Patents
400+
Lectures given

internationally

Prof. Michael Detmar 

CHIEF SCIENTIFIC OFFICER, IRÄYE

Current Positions

Professor of Pharmacogenomics, ETH Zurich, Institute of Pharmaceutical Sciences

Co-founder and Chief Scientific Officer at IRAYE Skincare

Visiting Professorships

Visiting Professor, Kitasato University, Japan (2018-present)

Visiting Professor of Pathology and of Dermatology, Harvard Medical School, Boston, USA (1993-1997)

Notable Roles

Election to the German National Academy of Sciences Leopoldina

Associate Professor of Dermatology, Harvard Medical School, Boston, USA

Assistant Professor of Dermatology, Steglitz Medical Center, Free University of Berlin

Elected member, Research Council of the Swiss National Science Foundation



Awards

2005 - Marion B. Sulzberger Memorial Award and Lectureship, American Academy of Dermatology

2006 - Jeffrey Schechner Memorial Lecture, Yale University

2007 - Rudi Kormane Lectureship, European Society for Dermatological Research

2020 - Lifetime Achievement Award in the field of Lymphatics from the Lymphatic Education and Research Network, USA

Current Positions

Resident and Principle Investigator, Clinic for Plastic and Hand Surgery, University Hospital Zürich

Co-founder and President of the Board of Directors at IRAYE Skincare


Notable Roles

PhD Thesis (Dr. Sc.) with Prof. Michael Detmar, Institute of Pharmaceutical Sciences, ETH Zurich

Medical training (M.D. degree) Aristotle University of Thessaloniki, Greece and Georg August Universität Göttingen, Germany

Awards

2021 - Filling the Gap Award, University of Zurich

2021 - Research Award, 57th Swiss Plastic Surgery Annual Meeting

2020 - Principal Investigator Award, Lipedema Foundation

2016 - 6th World Symposium for Lymphedema Surgery, Barcelona, Spain (invited inaugural keynote lecturer)

Epameinondas Gousopoulos 

HEAD OF PRODUCT DEVELOPMENT, IRÄYE

Our
products

Skincare as clean as the alpine environment it was made in.

100% plant-based, free of toxins and fragrances.